They have been pounding the pavements, training hard and racking up mile after mile.
Now with just a few days to go, the runners are going through their final preparations for the London Marathon.
Danny Clarkson is running in memory of his daughter Precious, who died after being born 13 weeks premature.
His wife Rebecca Clarkson, from Wakefield, said: “We lost our little girl which was a really difficult. The staff at Pinderfields Hospital did all they could and we have had friends whose children have been care for in the same unit.”
Mr Clarkson will be raising money for Baby Lifeline – a charity which buys much-needed maternity equipment for hospitals.
Wakefield College student experience manager Leigh Allsop will be raising money for the Willow Foundation, which helped him through his battle with cancer eight years ago.
Mr Allsop, 33, was diagnosed with stage 2B Hodgkin’s Lymphoma after discovering a tumour in his neck.
Following 12 cycles of chemotherapy, Mr Allsop was given the all-clear and has since been in remission.
He said: “I want to raise money for Willow after they set up a special day for me to have an all-expenses paid trip to the FA Cup final.
“This really helped to motivate me through my chemotherapy and I hope to support their continued efforts in supporting young adults through their illnesses.”
A team of seven runners will also be running to raise money for Wakefield Hospice.
Hannah Ball, 25, from Thornes, is running in memory of her mum and grandma who were both cared for at the hospice.
She said: “The time my mum spent in the hospice before she passed away was unbearable. The staff couldn’t have been more perfect.
“They comforted us when we were upset and made us smile when we thought we had forgotten how to.”
Mrs Ball will be joined by Kerry Bateman, 39, from Horbury; Claire Kendall, 37, from Middlestown; Chris Linley, 28, from Royston; and Duncan Schofield, 33, from Horbury.
Mark Phillips and Richard Foster will also be raising money for the hospice.
The marathon takes place on Sunday, April 26.