A driver became ill before his car hit another vehicle on Agbrigg Road.
Emergency services were called to the scene, close to Bowman Street, before police closed Agbrigg Road road just after 5pm today (Monday).
Police said the driver of a VW Golf is believed to have suffered a medical episode at the wheel before the vehicle collided with a Toyota Yaris.
The driver of the Golf was taken to hospital by ambulance.
The driver of the Yaris was not seriously injured.