A lorry has crashed into a railway bridge in Ackworth Moor Top.
Doncaster Road is closed between the junction with New Road and the Beverley Arms roundabout after the accident at around 2.10pm.
Emergency services and recovery vehicles remain at the scene.
The driver, a 60-year-old man, has been injured.
Motorists have been told to find alternative route and bus services are being diverted.