Highways England is suspending nearly 600 miles of roadworks from Friday, May 27 to leave 97 per cent of its road network free over the weekend.
In Yorkshire and the North East, the organisation is lifting 17 sets of roadworks, and has also completed 23 sets ahead of the break.
Just eight sets of roadworks will remain over the weekend.
Roads Minister Andrew Jones said: “We are delivering the biggest improvement to roads since the 1970s to improve journeys for drivers in the busiest periods and to create new capacity.
“We do not want work to stand in the way of families during their bank holiday getaway, so I am pleased roadworks are being removed at so many locations.”
Roadworks to be lifted include bridge works and a boundary fence renewal scheme at the M62 junction 33 to junction 34, near Pontefract.
At the M1 junction 41 to junction 42, near Wakefield, the smart motorway upgrade roadworks will also be suspended.
Roadworks that will be completed ahead of the weekend include fence renewal and bridge works at the M62 junction 32 to junction 31, near Castleford.
And at the M62 junction 31, near Castleford, nearly two miles of resurfacing works have been completed in time for the break.
Resurfacing renewal works at the M606 junction 3, near Bradford, will be lifted while sign work at the M621 from junction 7 to junction 4 near Leeds will also be suspended.
Bridge works at the M62 junction 33, near Pontefract, will remain in place to protect open excavations.
And on the M1 from junction 31 to junction 36, near Sheffield, 12 miles of roadworks with a 50mph speed limit restriction will need to remain in place to prevent unsafe manoeuvres.
Near Leeds, two miles of roadworks for sign lighting renewal at the M621 junction 2 to junction 3 are also being lifted.
For more information visit www.highways.gov.uk for more details.