The building on the corner of Providence Street and Northgate has been vacant since being closed in 2016.
Now the applicant, listed as a Mr Paymen Karimi from Horbury, had applied to open four retail units.
The planning officer said the plans would not cause any significant harm to the surrounding area, visually or otherwise.
The Post Office moved its operations from Providence Street into WH Smith on Trinity Walk in 2016.
The decision to close the main building was not a popular one, despite the opening hours being extended and across seven days a week.
Wakefield MP Mary Creagh even launched a petition to keep the old office open which was signed by hundreds.
But the Post Office said it was not commercially viable to keep it open.
The recent plans to convert the old Post Office building did not receive any objections.