Georgia Roche, the inaugural Woman of Steel, made her return to the side as the Tigers built on their opening-day win over Featherstone Rovers two weeks ago.
Roche was involved in the first try as she provided the pass for Hollie-Mae Dodd to cross and open the scoring.
Trinity had struggled to get out of their own half but responded well to going behind but were unable to make a mark on the scoreboard.
Leah Jones added a second Tigers try before Eva Izumi and Lucy Eastwood dotted down to give the Tigers a 16-0 advantage at the half-time whistle.
After a shaky start to the second period, Roche scored a brilliant solo try to claim Castleford's first points since the interval.
Dodd added her second try of the afternoon and then Shona Hoyle powered through the line to race 30 metres and score. Roche's conversion was the first successful one of the afternoon.
Roche provided another assist for Dodd as she crashed over for her hat-trick. Georgie Hetherington scored her first try for two years and soon after went over for her second of the game in the 79th minute.
It was Castleford's ninth and final try of the contest and was successfully converted by Jones.
Meanwhile, Featherstone Rovers had an afternoon to forget as they suffered a 72-0 defeat at the hands of reigning champions Leeds Rhinos.
The Rhinos claimed 14 tries in a dominant display with Ellie Oldroyd, Francesca Goldthorp, Adaoha Akwiwu and Hanna Butcher all scoring two tries each.
Scores from Zoe Hornby, Tara Moxon, Sophie Robinson, Chloe Kerrigan, Caitlin Beevers and Orla McCallion completed the scoring for Leeds.